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TSR-033 - CAS 2225940-96-3
TSR-033 - CAS 2225940-96-3
SKU:MF-0099621-01
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Product Details
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Bioactivity
TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-expressed with PD-1. It bolsters T cell function and augments PD-1 inhibition both in vitro and in vivo, demonstrating anti-tumor activity [1].
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Target
LAG-3
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Related Pathways
Immunology/Inflammation
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CAS Number
2225841
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies