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Molfinity

TTBK1/2-IN-2 - CAS 2857982-35-3

TTBK1/2-IN-2 - CAS 2857982-35-3

SKU:MF-0114632-01

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  • Bioactivity

    TTBK1/2-IN-2 (compound 9) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 384 nM and 175 nM, respectively. In human induced pluripotent stem cells (iPSC), TTBK1/2-IN-2 demonstrates a significant ciliogenesis phenotype.

  • Target

    Microtubule Associated

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    2857944

  • Molecular Formula

    C22H24N4O

  • Molecular Weight

    360.452

  • SMILES

    OC(C#CC=1C=CC=2NC3=C(C=4N=C(N=CC4CCC3)N)C2C1)(CC)CC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound