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TTBK1/2-IN-3 - CAS 2857982-34-2
TTBK1/2-IN-3 - CAS 2857982-34-2
SKU:MF-0114286-01
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Product Details
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Bioactivity
TTBK1/2-IN-3 (compound 10) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 579 nM and 258 nM, respectively. TTBK1/2-IN-3 can reduce the expression of primary cilia on the surface of human induced pluripotent stem cells (iPSC) .
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Target
Microtubule Associated
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Related Pathways
Cytoskeletal Signaling
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CAS Number
2857946
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Molecular Formula
C21H22N4O
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Molecular Weight
346.426
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SMILES
OC(C#CC=1C=CC=2NC3=C(C=4N=C(N=CC4CCC3)N)C2C1)(C)CC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound