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TTK inhibitor 3 - CAS 2820453-41-4

TTK inhibitor 3 - CAS 2820453-41-4

SKU:MF-0098656-01

Regular price $565.97 USD
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  • Bioactivity

    TTK inhibitor 3 (compound 25) is a selective inhibitor of TTK (Threonine Tyrosine Kinase) with an IC50 of 3.0 nM for TTK and 16.0 nM for CAL-51 cells. It inhibits tumor growth in CAL-51 xenograft models and TNBC (triple-negative breast cancer) PDX models.

  • Target

    Tyrosine Kinases

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    2820408

  • Purity

    0.9944

  • Molecular Formula

    C42H49N9O3

  • Molecular Weight

    727.9

  • SMILES

    O=C1C2=CC(=CN2CCN1C=3C(=CC=CC3CC)CC)C=4N=C(N=C5NC=CC54)NC6=CC=C(C=C6OC)N7CCC(C(=O)N8CC9(C8)CN(C)C9)CC7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound