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TTK/PLK1-IN-1 - CAS 1817791-70-0

TTK/PLK1-IN-1 - CAS 1817791-70-0

MF-0097805-01

$420.31 USD
$420.31 USD
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Product Details

  • Bioactivity

    TTK/PLK1-IN-1 (Formula I) is an inhibitor of threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1), with IC50 values of 7 nM and 72 nM, respectively. It regulates the spindle assembly checkpoint (SAC) and exhibits antitumor activity against triple-negative breast cancer (TNBC) .

  • Target

    Tyrosine Kinases, Kinesin, PLK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Cell Cycle/Checkpoint

  • CAS Number

    1817721

  • Purity

    0.9739

  • Molecular Formula

    C30H33N7O2

  • Molecular Weight

    523.63

  • SMILES

    O=C(NC=1C(=CC=CC1C)C)C=2C=CN3C4=NC(=NC=C4CCC23)NC5=CC=C(C=C5OC)N6CCNCC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound