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Tubulin inhibitor 49 - CAS 1023875-75-3
Tubulin inhibitor 49 - CAS 1023875-75-3
SKU:MF-0097859-01
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$45.13 USD
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$45.13 USD
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Product Details
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Bioactivity
Tubulin inhibitor 49 (Compound 18) is a tubulin polymerization inhibitor (IC50 = 48 μM) that disrupts the cellular microtubule network, arresting the cell cycle at G2 phase. It exhibits toxicity toward HeLa cells (IC50 = 8.8 μM) .
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Target
Microtubule Associated, Cell Cycle Arrest
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Related Pathways
Cytoskeletal Signaling, Cell Cycle/Checkpoint
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CAS Number
1023797
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Purity
0.9915
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Molecular Formula
C18H14F3N3OS
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Molecular Weight
377.38
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SMILES
O=C(NC=1C=CC(=CC1)C=2N=C(SC2)NC3=CC=CC(=C3)C(F)(F)F)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound