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Tubulin inhibitor 49 - CAS 1023875-75-3

Tubulin inhibitor 49 - CAS 1023875-75-3

SKU:MF-0097859-01

Regular price $45.13 USD
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  • Bioactivity

    Tubulin inhibitor 49 (Compound 18) is a tubulin polymerization inhibitor (IC50 = 48 μM) that disrupts the cellular microtubule network, arresting the cell cycle at G2 phase. It exhibits toxicity toward HeLa cells (IC50 = 8.8 μM) .

  • Target

    Microtubule Associated, Cell Cycle Arrest

  • Related Pathways

    Cytoskeletal Signaling, Cell Cycle/Checkpoint

  • CAS Number

    1023797

  • Purity

    0.9915

  • Molecular Formula

    C18H14F3N3OS

  • Molecular Weight

    377.38

  • SMILES

    O=C(NC=1C=CC(=CC1)C=2N=C(SC2)NC3=CC=CC(=C3)C(F)(F)F)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound