Tubulin polymerization-IN-43 - CAS 2773345-90-5

Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell cycle arrest and apoptosis in leukaemia cells. Tubulin polymerisation-IN-43 has multiple effects, promoting leukaemia cell cycle arrest in G2/M phase and apoptosis by targeting Colchicine sites to disrupt the cellular microtubule network.

Apoptosis, Microtubule Associated

Apoptosis, Cytoskeletal Signaling

2773250

0.9998

C17H13F4N3O

351.3

N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3

-20°C

Ice Packs

Small Compound