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Tubulin polymerization-IN-56 - CAS 2966790-98-5
Tubulin polymerization-IN-56 - CAS 2966790-98-5
SKU:MF-0158321-01
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Product Details
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Bioactivity
Tubulin Polymerization-IN-56 (compound 8l), an indazole derivative, potently inhibits tubulin polymerization by targeting the colchicine site, which induces cell cycle arrest and apoptosis. Additionally, this compound diminishes cell migration and significantly inhibits tumor growth in vivo [1].
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Target
Apoptosis, Others, Microtubule Associated
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Related Pathways
Apoptosis, Others, Cytoskeletal Signaling
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CAS Number
2966790-98-5
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Molecular Formula
C22H22ClN3O3
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Molecular Weight
411.88
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SMILES
Cl.N1=CC(=CC=C1C)C=2C=CC=3C=NN(C4=CC(OC)=C(OC)C(OC)=C4)C3C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound