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Tubulin polymerization-IN-61 - CAS 2758114-60-0

Tubulin polymerization-IN-61 - CAS 2758114-60-0

MF-0121488-01

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Product Details

  • Bioactivity

    Tubulin polymerization-IN-61 (Compound 9a), a tubulin polymerization inhibitor, disrupts the microtubule skeleton, arrests the cell cycle at the G2/M phase, induces Apoptosis, and impedes cancer cell migration and colony formation. This compound demonstrates antitumor efficacy in vivo within the 4T1 xenograft model [1].

  • Target

    Microtubule Associated, Apoptosis

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    2758114-60-0

  • Molecular Formula

    C22H21N3O5

  • Molecular Weight

    407.42

  • SMILES

    O(C)C=1C=C(N2C=3C(N=N2)=CC=C(C3)C4=CC(O)=C(OC)C=C4)C=C(OC)C1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound