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Tubulysin I - CAS 799822-10-9
Tubulysin I - CAS 799822-10-9
SKU:MF-0031803-01
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Product Details
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Bioactivity
Tubulysin I is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin I is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.
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Target
Microtubule Associated, ADC Cytotoxin
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Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
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CAS Number
799803
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Molecular Formula
C40H59N5O10S
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Molecular Weight
801.99
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SMILES
[C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)COC(C)=O)C(C)C)(OC(C)=O)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(O)=O)C)=O)=CS2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product