TUG-499 - CAS 1206629-08-4

TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39) . It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARγ, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes.

PPAR, GPCR

Endocrinology/Hormones, GPCR/G Protein, Metabolism, DNA Damage/DNA Repair

1206629-08-4

0.9993

C16H11Cl2NO2

320.17

C(#CC1=CC=C(CCC(O)=O)C=C1)C=2C=C(Cl)N=C(Cl)C2

-20°C

Ice Packs

Small Compound