TUL01101 - CAS 2411222-97-2

TUL01101, a potent, selective, and orally active inhibitor of JAK1, exhibits half-maximal inhibitory concentrations (IC50s) of 3 nM for JAK1, 37 nM for JAK2, 1,517 nM for JAK3, and 36 nM for TYK2. This compound is utilized in the research of rheumatoid arthritis.

Others, JAK

JAK/STAT signaling, Stem Cells, Others, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis

2411123

C22H25F2N5O2

429.46

C(=O)(N1CC2(C1)CCC(CC2)C=3N4C(=NC(NC(=O)C5CC5)=N4)C=CC3)[C@H]6C(F)(F)C6

-20°C

Ice Packs

Small Compound