Tutuilamide A - CAS 2756129-42-5

Tutuilamide A, a potent inhibitor of porcine pancreatic elastase (PPE) with an IC50 of 1.2 nM, also effectively inhibits human neutrophil elastase (HNE; IC50=0.73 nM) and kallikrein 7 (KLK7; IC50=5.0 nM) [1].

2756082

C51H69ClN8O12

1021.59

C([C@@H]1N2C(=O)[C@](CC[C@H]2O)(NC(=O)\C(=C\C)\NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC(C/C(=C/Cl)/C)=O)C)=O)[C@H](CC)C)=O)[C@@H](C)OC(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC3=CC=C(O)C=C3)N(C)C1=O)[H])C4=CC=CC=C4

-20°C

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Peptide