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TWIK-1/TREK-1-IN-2 - CAS 1440532-32-0
TWIK-1/TREK-1-IN-2 - CAS 1440532-32-0
SKU:MF-0147009-01
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$1,383.80 USD
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Product Details
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Bioactivity
TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values of 10.13 μM and 15.5 μM, respectively; additionally, it exhibits antidepressant properties [1].
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Target
Potassium Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
1440500
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Molecular Formula
C20H29F3N2O2
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Molecular Weight
386.45
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SMILES
C([C@@H](COC1=CC=C(C(F)(F)F)C=C1)O)N2CCC(CC2)N3CCCCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound