TX-1123 - CAS 157397-06-3

TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for COX2 and 15.7 μM for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.

Others, Src, PKA, PKC, EGFR, COX, CaMK

Angiogenesis, Others, Neuroscience, Immunology/Inflammation, Chromatin/Epigenetic, Cytoskeletal Signaling, JAK/STAT signaling, Tyrosine Kinase/Adaptors

157397-06-3

C20H24O3

312.4

C(C)(C)(C)C1=C(O)C(C(C)(C)C)=CC(C=C2C(=O)C=CC2=O)=C1

-20°C

Ice Packs

Small Compound