TX2-121-1 - CAS 1603845-42-6

TX2-121-1 targets HER3 for proteasome-mediated degradation to inhibit HER3-dependent signalling and growth.

Others, PROTACs, Akt, EGFR, ERK

Angiogenesis, JAK/STAT signaling, Others, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, PROTAC, PI3K/Akt/mTOR signaling, MAPK

1603797

C42H52N8O3

716.91

C(C[C@H](C(NCCN1CCC(CC1)N2C=3C(C(=N2)C4=CC(NC(C=C)=O)=C(OC5=CC=CC=C5)C=C4)=C(N)N=CN3)=O)C)C67CC8CC(C6)CC(C7)C8

-20°C

Ice Packs

Small Compound