TY-011 - CAS 1389439-77-3

TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.

Aurora Kinase

Cell Cycle/Checkpoint, Chromatin/Epigenetic

1389439-77-3

C18H16ClN5

337.81

ClC=1C=CC=CC1C2=NC=3C(=NNC3C)NC=4C=C(N=CC24)CC

-20°C

Ice Packs

Small Compound