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Molfinity

Tyk2-IN-16 - CAS 3010874-30-0

Tyk2-IN-16 - CAS 3010874-30-0

MF-0121494-01

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Product Details

  • Bioactivity

    Tyk2-IN-16 is a potent and selective TYK2 inhibitor with an IC50 of less than 10 nM for TYK2-JH2. It inhibits pSTAT4 in NK92 cells with an IC50 of under 10 nM (WO2023220046A1; compound 184) [1].

  • Target

    JAK

  • Related Pathways

    Stem Cells, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis

  • CAS Number

    3010874-30-0

  • Molecular Formula

    C20H20F2N8O

  • Molecular Weight

    426.42

  • SMILES

    N(C(C)=O)C=1C=C2C(C(=NN2C=3N=C(C(C)(F)F)C=CN3)N4CC(C#N)(C)CC4)=CN1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound