Tyk2-IN-20 - CAS 3058568-08-1

Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.

JAK

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic

3058568-08-1

C24H25N7O2

443.5

C(#N)[C@@]1(C(=O)N(C[C@H]1C)C=2C=3N(C=C(N2)C4=CN(N=C4)C5CC6(C5)COC6)N=CC3)C7CC7

-20°C

Ice Packs

Small Compound