Molfinity

TYK2 ligand 2 - CAS 2924460-80-8

SKU:MF-0114682-01

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Product Details

Bioactivity
TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.
Target
JAK
Related Pathways
JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis
CAS Number
2924372
Molecular Formula
C24H20FN7O4
Molecular Weight
489.458
SMILES
O=C(O)C1=CN=C(C=C1)NC2=NC=C(C(=O)NC)C(=C2)NC3=CC=CC(C4=NC=C(F)C=N4)=C3OC
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
PROTAC