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Type II TRK inhibitor 1 - CAS 2937543-72-9

Type II TRK inhibitor 1 - CAS 2937543-72-9

MF-0146103-01

$1,252.17 USD
$1,252.17 USD
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Product Details

  • Bioactivity

    Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) fusion protein variants as well as the wild type. It demonstrates notable antiproliferative effects on Ba/F3 cells expressing CD74-TRKA G667C and ETV6-TRKC G696C, with half-maximal inhibitory concentrations (IC50s) of 6 nM and 1.7 nM, respectively [1].

  • Target

    Trk receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    2937462

  • Molecular Formula

    C35H33F3N8O3

  • Molecular Weight

    670.68

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound