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Molfinity

TYRA-300 - CAS 2800223-30-5

TYRA-300 - CAS 2800223-30-5

MF-0095519-01

$393.98 USD
$393.98 USD
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Product Details

  • Bioactivity

    TYRA-300 is an oral and selective FGFR3 inhibitor with an IC50 value of 11 nM and 25-fold, 14-fold, and 36-fold selectivity for FGFR1, FGFR2, and FGFR4, respectively, in the Ba/F3 cell line for the treatment of metastatic uroepithelial carcinomas (mUCs) and chondrodysplasia.

  • Target

    FGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    2800223-30-5

  • Purity

    0.9966

  • Molecular Formula

    C25H24Cl2N6O3S

  • Molecular Weight

    559.47

  • SMILES

    S(C)(=O)(=O)N1CC2(CN(C2)C3=CC=C(C=N3)C=4C=5C(NN4)=CC=C(O[C@H](C)C=6C(Cl)=CN=CC6Cl)C5)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound