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Tyrphostin AG 879 - CAS 148741-30-4

Tyrphostin AG 879 - CAS 148741-30-4

MF-0013630-01

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 with an IC50 of 1 μM, demonstrating 100- and 500-fold higher selectivity for ErbB2 over EGFR and PDGFR, respectively.

  • Target

    PDGFR, Apoptosis, HER, EGFR, Trk receptor

  • Related Pathways

    JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis

  • CAS Number

    148707

  • Purity

    0.9905

  • Molecular Formula

    C18H24N2OS

  • Molecular Weight

    316.46

  • SMILES

    CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound