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TZEP7 - CAS 2566714-41-6
TZEP7 - CAS 2566714-41-6
SKU:MF-0113749-01
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Product Details
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Bioactivity
TZEP7 functions as an EGFR kinase inhibitor in cancer cells. It exhibits cytotoxicity and induces apoptosis within these cells. TZEP7 downregulates the anti-apoptotic protein Bcl-2, upregulates the pro-apoptotic protein Bax, and increases caspase levels. This compound holds potential for research in anticancer drug development.
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Target
EGFR, Caspase, Apoptosis, Bcl-2 Family
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Related Pathways
JAK/STAT signaling, Proteases/Proteasome, Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis
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CAS Number
2566667
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Molecular Formula
C27H19ClFNS
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Molecular Weight
443.963
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SMILES
C(\C#CC1=CC=CC=C1)=C/2\SC(=CC(=NC2)C3=CC(C)=C(F)C=C3)C4=CC=C(Cl)C=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound