UA 62784 - CAS 313367-92-9

Inhibitor of microtubule polymerization in vitro. Interacts with tubulin dimers and promotes the accumulation of mammalian cells in apoptosis. Potentiates antiproliferative effects of vinblastine in H2B-GFP HeLa cells. Originally thought to inhibit CENP-E ATPase activity.

Others, Microtubule Associated, Apoptosis, Kinesin

Cytoskeletal Signaling, Others, Apoptosis

313266

C23H15NO3

353.37

O=C1C=2C(C=3C1=CC=CC3)=C(C=CC2)C=4OC(=CN4)C5=CC=C(OC)C=C5

-20°C

Ice Packs

Small Compound