UBX-382 - CAS 2884554-45-2

UBX-382 is an orally administered proteolysis-targeting chimera (PROTAC) designed to target BTK and disrupt B-cell receptor signaling. It demonstrates enhanced degradation of both wild-type and mutant BTK proteins, exhibiting anti-cancer effects in murine xenograft models using TMD-8 cells [1].

BTK

Angiogenesis, Tyrosine Kinase/Adaptors

2884554-45-2

C42H44N10O4

752.86

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CCC(CN5CC=6C(CC5)=CC=C(NC=7N=C8C(=CN7)C(NC9=C(C)C=CC=C9C)=NN8C)C6)CC4

-20°C

Ice Packs

Small Compound