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UC-857993 - CAS 487001-04-7
UC-857993 - CAS 487001-04-7
SKU:MF-0143885-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts (MEFs) .
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Target
Others, Ras, ERK
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Related Pathways
MAPK, Others, GPCR/G Protein
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CAS Number
487001-04-7
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Molecular Formula
C25H22ClNO2
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Molecular Weight
403.9
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SMILES
C(O)(=O)C=1C=C2C=3N(C(C4C2C=CC4)C5=C(Cl)C=CC=C5)CC6C(C3C1)C=CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound