UCL 2077 - CAS 918311-87-2

UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker, with IC50 of 500 nM in hippocampal neurons in culture, having minimal effects on Ca2+ channels, action potentials, input resistance, and the medium afterhyperpolarization.

Potassium Channel, Others

Membrane transporter/Ion channel, Others

918222

0.9958

C25H22N2

350.46

C(NCC=1C=CC=NC1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound