UGT1A1-IN-1 - CAS 2097024-37-6

UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].

UGT

Metabolism

2097024-37-6

C22H19NO3

345.39

O=C1C=2C3=C(C(=CC2)C4=CC=C(O)C=C4)C=CC=C3C(=O)N1CCCC

-20°C

Ice Packs

Small Compound