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Molfinity

UKH-1114 - CAS 2113664-14-3

UKH-1114 - CAS 2113664-14-3

MF-0112245-01

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Product Details

  • Bioactivity

    UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.

  • Target

    Sigma receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    2113647

  • Molecular Formula

    C22H24F3NO

  • Molecular Weight

    375.43

  • SMILES

    FC(F)(F)C1=CC=C(C=C1)C=2C=CC3=C(C2)C4N(CCCO)CCCC3C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound