UMB-32 - CAS 1635437-39-6

UMB-32 is a potent and selective BRD4 inhibitor, demonstrating an affinity for BRD4 with a dissociation constant (K d) of 550 nM and an inhibitory concentration 50 (IC 50) of 637 nM. Moreover, UMB-32 exhibits effectiveness against TAF1, a bromodomain-containing transcription factor [1].

Epigenetic Reader Domain, Others

Chromatin/Epigenetic, Others

1635392

C21H23N5O

361.44

N(C(C)(C)C)C1=C(N=C2N1C=CN=C2)C3=CC=C(C=C3)C=4C(C)=NOC4C

-20°C

Ice Packs

Small Compound