UNC9426 - CAS 3051784-94-9

UNC9426 is an orally active, potent and selective TYRO3 inhibitor with an IC50 of 2.1 nM. It reduces platelet aggregation without prolonging bleeding time and blocks TYRO3-dependent functions in tumour cells and macrophages, making it suitable for studying thrombosis and platelet aggregation.

Platelet aggregation, TAM Receptor

Others, Tyrosine Kinase/Adaptors

3051681

0.98051

C32H34F6N6O

632.642

N(C=1N=C2C(C(=CN2[C@H]3CC[C@H](O)CC3)C4=CC=C(CN5CCN(C)CC5)C=C4)=CN1)C6=CC(C(F)(F)F)=CC(C(F)(F)F)=C6

-20°C

Ice Packs

Small Compound