UPSEM 817 tartrate - CAS 2341833-14-3

Selective ultrapotent PSEM (uPSEM) agonist for α7L131G, Q139L, Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channel agonist (EC50 values are 0.3 and 0.5 nM, respectively) . Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg) .

Others

Others

2341816

C20H25N3O7

419.434

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCCOc1cnc2cc3C4CC(CNC4)c3cc2n1 |THB:27:26:21:23.24.25,18:19:21:23.24.25|

-20°C

Ice Packs

Small Compound