Urantide acetate (669089-53-6 free base) - CAS 9007-83-4

Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) . Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors) .

Neurotensin Receptor

GPCR/G Protein

8920

0.9922

C53H70N10O14S2

1135.31

CC([C@@H](C(O)=O)NC([C@@H]1CSSC(C)([C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)Cc2ccc(O)cc2)=O)CCCN)=O)Cc(c[nH]3)c4c3cccc4)=O)Cc5ccccc5)=O)NC([C@H](CC(O)=O)N)=O)C)=O)C.CC(O)=O

-20°C

Ice Packs

Peptide