URAT1-IN-14 - CAS 2516232-89-4

URAT1-IN-14 is a potent and orally active inhibitor of uric acid transporter 1 (URAT1) . It demonstrates an IC50 value of 0.72 μM for inhibiting human URAT1 in HEK293 cells and exhibits low cytotoxicity in Hep-G2 cells. URAT1-IN-14 reduces uric acid levels in a hyperuricemia mouse model and is applicable in research on hyperuricemia and gout.

OAT

Membrane transporter/Ion channel

2516139

C19H19NO3S

341.42

O=C(O)C1(SC=2C=CC=CC2N3C=4C=CC=CC4OCC3)CCC1

-20°C

Ice Packs

Small Compound