Urease-IN-20 - CAS 2998940-98-8

Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 μM for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and γH2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.

Reactive Oxygen Species, Apoptosis, Antibacterial

Apoptosis, NF-κB, Immunology/Inflammation, Metabolism, Microbiology/Virology

2998834

C14H8FNO2Se

320.18

O=C(OC1=N[Se]C=2C=CC=CC12)C=3C=CC=C(F)C3

-20°C

Ice Packs

Small Compound