Ureidopropionic acid - CAS 462-88-4

Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in uracil metabolism, produced from dihydrouracil by the enzyme dihydropyrimidase and further decomposed to beta-alanine by beta-ureidopropionase. It is a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with severe toxicity to the antineoplastic agent 5-fluorouracil.

Endogenous Metabolite

Metabolism

370

0.9985

C4H8N2O3

132.12

NC(=O)NCCC(O)=O

-20°C

Ice Packs

Natural Product