Urolithin B - CAS 1139-83-9

Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass. Urolithin B has anti-inflammatory and antioxidant effects.

Endogenous Metabolite, ERK, AMPK, JNK, NF-κB, Akt

MAPK, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Metabolism, Cytoskeletal Signaling, NF-κB

1139-83-9

0.9964

C13H8O3

212.2

Oc1ccc2c(c1)oc(=O)c1ccccc21

-20°C

Ice Packs

Natural Product