USP28-IN-3 - CAS 2931509-14-5

USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

DUB

Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

2931490

0.9992

C23H20Cl2N2O3S

475.39

O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CCNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C

-20°C

Ice Packs

Small Compound