USP7-797 - CAS 2413944-70-2

USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency (IC50=0.44 nmol), it is effective on both wild-type and mutant p53 tumor cells, and can significantly inhibit the growth of tumor cells and induce apoptosis.

DUB

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination

2413872

0.9618

C27H28ClN3O3S

510.05

CC1(C)C2C1C(=O)N(CC=3SC=4C(C3)=NC=CC4C5=C(C[C@@H]6CNCCO6)C(C)=CC(Cl)=C5)C2=O

-20°C

Ice Packs

Small Compound