USP7-IN-16 - CAS 2166587-77-3

USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.

Others, DUB

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Ubiquitination

2166507

C43H45N7O6S

787.93

O=C1C2=C(N(C=C2)C3=CC(OC)=CC(OC)=C3)N=CN1CC4(O)CCN(C(=O)[C@H]5[C@@H](CN(C(=O)C=6SC(=NC6C)C=7C=CC(C)=NC7)CC5)C8=CC=CC=C8)CC4

-20°C

Ice Packs

Small Compound