V-161 - CAS 69570-95-2

V-161 is an orally active Na+-V-ATPase inhibitor with an IC50 of 144 nM. Under alkaline conditions, V-161 inhibits Enterococcus hirae and vancomycin-resistant Enterococcus faecium (VRE), with MIC values of 4 μg/mL for both. Additionally, V-161 can inhibit the colonization of VRE in the mouse small intestine.

ATPase, Antibacterial

Membrane transporter/Ion channel, Microbiology/Virology

69473

C16H17N3

251.326

N=1C2=CC(=CC=C2NC1C=3C=CC(=CC3)N(C)C)C

-20°C

Ice Packs

Small Compound