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VA-K-14 hydrochloride - CAS 1171341-19-7
VA-K-14 hydrochloride - CAS 1171341-19-7
SKU:MF-0040409-01
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$50.37 USD
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$50.37 USD
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Product Details
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Bioactivity
VA-K-14 hydrochloride (VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
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Target
TSH Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
1171315
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Purity
0.9937
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Molecular Formula
C18H16ClN3S
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Molecular Weight
341.86
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SMILES
Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound