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Molfinity

VA-K-14 hydrochloride - CAS 1171341-19-7

VA-K-14 hydrochloride - CAS 1171341-19-7

SKU:MF-0040409-01

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  • Bioactivity

    VA-K-14 hydrochloride (VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.

  • Target

    TSH Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    1171315

  • Purity

    0.9937

  • Molecular Formula

    C18H16ClN3S

  • Molecular Weight

    341.86

  • SMILES

    Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound