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Val-Cit-PAB-Exatecan TFA - CAS 2928571-44-0
Val-Cit-PAB-Exatecan TFA - CAS 2928571-44-0
SKU:MF-0121949-01
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Product Details
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Bioactivity
Val-Cit-PAB-Exatecan TFA (Val-Cit-PAB-DX8951 TFA) forms part of an antibody-drug conjugate (ADC) . The compound consists of the DNA topoisomerase I inhibitor DX-8951 and a protease-degradable ADC linker.
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2928571-44-0
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Molecular Formula
C45H50F4N8O11
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Molecular Weight
954.92
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SMILES
C(C(O)=O)(F)(F)F.N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound