Valproic Acid-d4 - CAS 87745-17-3

Valproic Acid-d4 is a deuterated compound of Valproic Acid. Valproic Acid has a CAS number of 99-66-1. Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A (sc-3511) in the inhibition of histone deacetylase.

Mitophagy, Autophagy, Gamma-secretase, HIV Protease, Endogenous Metabolite, HDAC

DNA Damage/DNA Repair, Neuroscience, Proteases/Proteasome, Metabolism, Microbiology/Virology, Autophagy, Chromatin/Epigenetic, Stem Cells

87745-17-3

C8H12D4O2

148.24

C(O)(=O)C(C([2H])([2H])CC)C([2H])([2H])CC

-20°C

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