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Molfinity

Vamotinib - CAS 1416241-23-0

Vamotinib - CAS 1416241-23-0

MF-0016028-01

$112.75 USD
$112.75 USD
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Product Details

  • Bioactivity

    Vamotinib (PF-114) is an orally active and specific tyrosine kinase inhibitor with antiproliferative and antitumour activity.Vamotinib inhibits the phosphorylation of BCR/ABL and BCR/ABL-T315I, which promotes apoptosis. Vamotinib is used to study drug-resistant Philadelphia chromosome-positive (Ph+) leukaemia and Alzheimer's disease.

  • Target

    Apoptosis, Tyrosine Kinases, Bcr-Abl

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Cytoskeletal Signaling

  • CAS Number

    1416218

  • Purity

    0.9964

  • Molecular Formula

    C29H27F3N6O

  • Molecular Weight

    532.56

  • SMILES

    CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3nnc4ccccn34)cc2C(F)(F)F)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound