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Vandetanib hydrochloride - CAS 524722-52-9

Vandetanib hydrochloride - CAS 524722-52-9

MF-0140678-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. It also exhibits activity against VEGFR3/FLT4 tyrosine kinase activity (IC50 = 110 nM) and EGFR/HER1 (IC50 = 500 nM) [1].

  • Target

    Apoptosis, VEGFR, Autophagy, Others

  • Related Pathways

    Apoptosis, Autophagy, Tyrosine Kinase/Adaptors, Others, Angiogenesis

  • CAS Number

    524661

  • Molecular Formula

    C22H25BrClFN4O2

  • Molecular Weight

    511.81

  • SMILES

    Cl.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound