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Vandetanib trifluoroacetate - CAS 338992-53-3

Vandetanib trifluoroacetate - CAS 338992-53-3

MF-0048809-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Vandetanib trifluoroacetate (D6474 trifluoroacetate) is an orally active and potent VEGFR2/KDR tyrosine kinase inhibitor with an IC50 value of 40 nM. It also inhibits VEGFR3/FLT4 and EGFR/HER1, with IC50 values of 110 nM and 500 nM respectively.

  • Target

    Others, Autophagy, Apoptosis, VEGFR

  • Related Pathways

    Angiogenesis, Others, Tyrosine Kinase/Adaptors, Autophagy, Apoptosis

  • CAS Number

    338936

  • Molecular Formula

    C24H25BrF4N4O4

  • Molecular Weight

    589.386

  • SMILES

    OC(=O)C(F)(F)F.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound