Varenicline Hydrochloride - CAS 230615-23-3

Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is recognized as the principal mediator of nicotine dependence, and its pharmacological effect is critical in modulating addictive behaviors associated with nicotine exposure. Varenicline Hydrochloride (CP 526555) blocks the direct agonist effects of nicotine on nicotinic acetylcholine receptors while simultaneously stimulating these receptors in a more moderate and controlled manner, making it a widely used research compound in smoking cessation.

Others, AChR

Others, Neuroscience

230589

0.99854

C13H14ClN3

247.72

Cl.N1=CC=NC2=CC3=C(C=C12)C4CNCC3C4

-20°C

Ice Packs

Small Compound