Molfinity

Varlitinib - CAS 845272-21-1

SKU:MF-0094545-01

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Size 50 mg 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg

Product Details

Bioactivity
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50 values of 7 nM for HER1, 2 nM for HER2, and 4 nM for HER4.
Target
EGFR, HER
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
CAS Number
845250
Purity
0.997
Molecular Formula
C22H19ClN6O2S
Molecular Weight
466.94
SMILES
C[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound